The regular success rate in egg donation procedure varies about 50%. Anyway there are aspects that may improve the possibility of success. First of all the experience of the doctors. The second is the condition of the donored eggs. If the donors are young the success possibility rises conciderably. And the final point is the usage of the original technologies. Just a minority clinics offer all the three benefits. One of them is AVA-Peter, a Russian-Finnish fertility clinics in Saint Petersburg. The next describes treatment they perform. This made them able to reach a 70% success rate in egg donation in first half of 2009.
Egg donation involves the first one is called an an egg donor and an egg recipient. The egg donor goes through IVF process to make her ovaries eggs. These egg cells are then inspermated in the lab by the semen of the egg recipient's husband partner (or a sperm donor). Thefertilised eggs become embryos, and one or a pair of them are introduced back into the uterus of the egg recipient to produce a pregnancy.
Differences between IVF and IVF with egg donation
The major difference between 'standard IVF' and 'egg donation IVF' is that a single more person is required to help make a pregnancy. This is the egg donor, whose eggs are used if the would-be mother (the egg recipient) cannot make use of her own eggs to get pregnant. The following is a complete explanation of all the programme steps.
Synchronising the menstrual cycles
Both the egg donor & the egg recipient should be at the beginning of their menstrual cycles which is needed to commence egg donation treatment process. In case if no longer have a regular menstrual cycle, we can induce it's beginning at the tijme we need.This is made by prescribing birth control pillowsto the donor and the recipient according to the agreed time-table. The tablets course is stopped on the same date by both the donor the recipient, resulting in a menstruation in both ladies.
The egg donor's treatment
After the egg donor's period begins, she has an ultrasound inspection of the womb and the ovaries to assure the ovaries are inactive and the womb lining is thin enough. Your egg donor afterwards undertakes medication to stimulate her ovaries to create egg cells. After 10 days, she takes an additional hormone to make the egg cells prepared for harvesting. Egg collection is performed by aspirating the cells from the follicles by a needle incerted into the ovary through the vagina. Her mission is now over.
The egg recipient's treatment
Egg recipients may or may not have a ordinary menstrual cycle. Once the period is induced by the tablets, you may have one or in some cases more injections of a 'down-regulating' medicine to make certain best synchronisation with your donor. Typicaly, you will afterwards have a inspection to check that the lining of your uterus is thin enough and that there are no cysts right before the beginning of the treatment course. This includes taking oestrogen pills, cream or patches to build up your womb membrane again. Five days before the intended day for Embryo Transfer, you start taking progesterone as well as oestrogen.
Insemination and embryo transfer
The donor eggs gathered are fertilised with the sperm of the your partner or a donor. They are grown in our laboratory for three or (more often) five days. For the duration of this phase, they go on with dividing and grow. At five days old, embryos turn out to be| blastocysts. By this stage, our experienced embryologists can determine which embryos have the most viable quality. On the date of embryo transfer, one or two of the excellent quality embryos are introduced through the cervical canal incide the egg recipient's uterus using a thin, soft plastic catheter. This process is usually fast and provides no pain.
Following the embryo incertion, you carry on with taking oestrogen and progesterone pills for two weeks and then take a pregnancy test. If the test shows positive result, you must have a scan to confirm the pregnancy two weeks after. If a 'fetal pole' is visible on the scan, this gives clinical proof of your pregnancy.
At AVA-Peter, we had a 60% pregnancy rate in 2008. It was the confirmed clinical pregnancy rate after replacing 2 fresh (not frozen) embryos at the 5-day-old blastocyst development stage. The number of children born through egg donation is growing each year as more infertile ladies become aware of this form of treatment.
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